Personalized Drug Screening for Patients with Age-related Macular Degeneration using iPSC-RPE

Grant Project Details:

Awardee:
Deborah Ferrington, PhD
Timeframe:
2019-2021
Location:
University of Minnesota | Minneapolis, MN
Amount:
$250,000
Status:
In Process
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Grant Location

University of Minnesota
2001 6th Street SELions Research Building
Minneapolis, MN 55455

Grant Description

Age-related macular degeneration (AMD) is a chronic disease that causes central vision loss and affects one's ability to read, drive, and recognize faces. There are currently no treatments for “dry” AMD, which includes ~80% of AMD patients in Minnesota. Dry AMD is associated with death of the retinal pigment epithelial (RPE) cells that is largely due to a loss in mitochondrial function.The overall goal of this research is to develop a therapy for patients with dry AMD by identifying drugs that will enhance mitochondrial function, thereby preserving the RPE.

Research Focus: age-related macular degeneration

Grant Awardee Biography

image of Deborah Ferrington