Activating the Hippo pathway effector YAP to augment liver regeneration

Grant Project Details:

Awardee:
Rory Smoot, MD
Timeframe:
2020-2022
Tags:
Location:
Mayo Clinic | Rochester, MN
Amount:
$250,000
Status:
In Process
Explore all RMM grants awarded since inception

Grant timeline: proposal, updates, reports

Grant Location

Mayo Clinic
Rochester, MN

Grant Description

The goal of this proposal is to speed up liver regeneration by activation a regeneration pathway with a drug treatment. This will be tested in multiple models, including models in which regeneration is not as good at baseline. Positive results would provide a potential treatment to improve liver function in patients suffering from liver failure.

Grant Awardee Biography

image of Rory Smoot, MD