Development of a chimeric antigen receptor T cell therapy platform at the Mayo Clinic

The goal of this project is to establish the infrastructure for the development of chimeric antigen receptor T (CART) cell therapy at the Mayo Clinic. CART cell therapy has emerged as a potent and potentially curative modality for the treatment of cancer. The technology engineers T cells to make them recognize cancer cells and therefore can be a platform used for the treatment of multiple solid and hematological malignancies. The ultimate goal is to develop a regenerative medicine service line using engineered T cells for the treatment of cancer.