Human glial progenitor cells for radiation‐induced brain injury

Grant Project Details:

Awardee:
Terry Burns, MD, PhD
Timeframe:
2020-2022
Tags:
Location:
Mayo Clinic | Rochester, MN
Amount:
$250,000
Status:
In Process
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Grant Location

Mayo Clinic
Rochester, MN

Grant Description

Brain irradiation is the standard of treatment for most brain tumors. Irradiating the brain prolongs patient survival, but often results in long term memory and functional impairments. These deficits are driven by radiation injury to myelinating cells, oligodendrocytes. One method to prevent deficits is to replace myelin by transplanting in new stem cells to the brain. We will test the safety and effectiveness of human glial cells to protect the brain in a model of radiation‐induced brain injury during therapy for brain cancer.

Grant Awardee Biography

image of Terry Burns, MD, PhD