Allogeneic platform for regenerative cell therapy by non-viral gene knockdown

Grant Project Details:

Awardee:
Andrew Lewis, PhD
Timeframe:
2021-2022
Location:
Luminary Therapeutics | Minneapolis, MN
Amount:
$88,443
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Grant timeline: proposal, updates, reports

Grant Location

Luminary Therapeutics
Minneapolis, MN

Grant Description

The goal of this project is develop a platform for engineering cells from non-autologous sources for cell therapy. We will use a transposon-based non-viral gene editing system that is safer, less expensive, and bypasses regulatory burdens compared to more common similar methods. This allogeneic platform will provide an off-the-shelf source for cell therapy that can be mass-manufactured to higher and more consistent release criteria than autologous sources.