Androgen Receptor Blockade to Augment Liver Regeneration

A liver resection, or hepatectomy, is a surgical procedure to remove part of the liver. Post-hepatectomy liver failure is a major complication, with no approved treatments currently available. This project focuses on repurposing an FDA-approved drug to enhance liver regeneration, addressing a significant unmet need for patients undergoing liver resection. Researchers will assess the efficacy and safety of this approach, ensuring it does not promote tumor growth. Successful completion of these studies will pave the way for clinical trials, potentially offering a new therapeutic option to prevent or treat post-hepatectomy liver failure and significantly improve patient outcomes.