A Novel Combined Allogeneic and Autologous Cell Therapy for Meniscus Tissue Repair

Grant Project Details:

Awardee:
Daniel Saris, MD, PhD
Timeframe:
2024-2026
Location:
Mayo Clinic | Rochester, MN
Amount:
$200,000
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Grant Location

Mayo Clinic
Rochester, MN

Grant Description

Despite advanced surgical techniques, meniscus repair remains a significant clinical challenge due to high failure rates and chronic disability among young patients. This project aims to address this issue through a novel, one-stage cell therapy combining allogeneic adipose-derived mesenchymal stem cells and autologous meniscus cells to promote regeneration. This therapy builds on the researchers' pioneering work with a similar approach for cartilage injuries, which showed promising results in clinical trials. The anticipated outcome is a paradigm shift in meniscus injury management, significantly reducing long-term disability and improving quality of life for young patients.