RMM Grants Awarded

See where grants have been awarded across Minnesota.
image of Steven Moran, MD
Steven Moran, MD
Regenerative strategy for volumetric muscle loss and functional recovery
The main goal of the project is to develop a therapeutic strategy for the regeneration of muscle volume and recovery of function after traumatic…
2020-2022
image of Brian Fife, PhD
Brian Fife, PhD
Generating and protecting human iPS designer islets for the treatment of type 1 diabetes
Autoimmune or Type 1 diabetes (T1D) results from the immune‐mediated destruction of insulin producing beta cells in the pancreas islets. In this…
2020-2022
image of Terry Burns, MD, PhD
Terry Burns, MD, PhD
Human glial progenitor cells for radiation‐induced brain injury
Brain irradiation is the standard of treatment for most brain tumors. Irradiating the brain prolongs patient survival, but often results in long…
2020-2022
image of Rory Smoot, MD
Rory Smoot, MD
Activating the Hippo pathway effector YAP to augment liver regeneration
The goal of this proposal is to speed up liver regeneration by activation a regeneration pathway with a drug treatment. This will be tested in…
2020-2022
image of Ilana Chefetz Menaker, PhD
Ilana Chefetz Menaker, PhD
Ovarian mesenchymal stem cells
Young women who undergo chemotherapy for cancer may face infertility. Our experiments are designed to learn how chemotherapy affects the ovaries.…
2020-2022
image of Martin Rodriguez‐Porcel, MD
Martin Rodriguez‐Porcel, MD
Understanding the interaction of stem cells and scaffolds with host tissue: implications of regenerative medicine
Stem cells have the potential to rebuild damaged tissues. Since most tissues are three dimensional, a molecular "scaffold" is often used to place…
2020-2022
image of Dan Dragomir-Daescu, PhD
Dan Dragomir-Daescu, PhD
Novel flow diverter for hemorrhage control using innovative magnetic nanotechnology
The goal of the proposed study is to use a pig model of hemorrhage to investigate the ability of our novel technologies (magnetic intravascular…
2020-2022
image of David Deyle, MD
David Deyle, MD
Treating osteogenesis imperfecta by inhibiting the PRC2 complex
The goal of this proposal is to develop a new strategy for skeletal regeneration in patients who have osteogenesis imperfecta (OI) or brittle bone…
2020-2022
image of Sunny Chan, PhD
Sunny Chan, PhD
Strategies for producing muscle stem cells
Muscular dystrophies are a group of chronic disorders characterized by progressive loss of muscle functions that unfortunately have no cure. Stem…
2020-2022
image of Patricia Devaux, PhD
Patricia Devaux, PhD
Concurrent gene editing and reprogramming of sickle cell disease fibroblasts using dual measles virus vectors
We have developed a new technology to reprogram human cells to go back to a state from which they can then develop into other kinds of cells. Our…
2020-2022
image of Emilyn Alejandro, PhD
Emilyn Alejandro, PhD
Placental mTOR Regulation of Pancreatic Endocrine Cells
Type 2 diabetes is the most common chronic disease, but the search for causes and preventative treatment has largely failed. Our grant seeks to…
2020-2022
image of Atsushi Asakura, PhD
Atsushi Asakura, PhD
Angiogenic therapy for muscular dystrophy
Duchenne Muscular Dystrophy (DMD) is caused by mutations in the dystrophin gene, which normally functions to maintain muscle membrane integrity and…
2020-2022