Joint stiffening (arthrofibrosis) is a debilitating complication with limited treatment options that is observed in a substantial subset of patients…
See where grants have been awarded across Minnesota.
Isobel Scarisbrick, PhD
Our goal is to develop a new treatment strategy that improves outcomes in individuals with chronic spinal cord injury. Studies will contribute to the…
2021-2023
Brenda Ogle, PhD
The clinical prognosis for patients with hypertrophic cardiomyopathy (HCM) is very poor and the only long-term alternative is heart transplant. Our…
2021-2023
Walter Low, PhD
The goal of this research is to facilitate the generation of human organs and cells for transplantation and repair of the human body. The generation…
2021-2023
Harald Junge, PhD
Retinal vascular diseases, e.g., diabetic retinopathy, are a leading cause of blindness and place a significant burden on individual patients as well…
2021-2023
Daniel Garry, MD, PhD
Cardiovascular diseases are common and deadly. It is estimated that the U.S. has limited blood supply for those that require transfusions (there are…
2021-2023
Alfonso Eirin, MD
Obesity remains a significant health problem that affects above 30% of Minnesotans. Obesity increases susceptibility to injury by interfering with…
2021-2023
Jason Doles, PhD
Neuromuscular diseases (NMDs) are life-altering conditions typically resulting in disability, poor quality of life, and eventual long-term dependency…
2021-2023
Sanjay Mirsa, MD
In the US, ~726,000 patients have end-stage renal disease (ESRD) requiring chronic hemodialysis, which will double in the coming decade. Optimal…
2021-2023
Atta Behfar, MD, PhD
1. Deployment of scalable and affordable regenerative solutions for patients who have experienced heart attack.
2. Establishment of safety for a…
2021-2023
Timothy O'Brien, DVM, PhD
We have developed a technically simple, scalable, cGMP‐compatible method to generate hyaline cartilage from human induced pluripotent stem cells.…
2020-2021
Wesley Wierson, PhD
LEAH Labs is bringing regenerative immunotherapy to dogs. We use gene editing to enable the translation of cell therapies from successful…
2020-2021