Development of inducible immunodeficient swine
Grant Project Details:
Immunodeficient swine have tremendous potential in basic and pre-clinical research; however, difficulties in propagation have impeded commercial availability. As a solution, we propose to build and test a conditional rescue cassette to pair with our RAG2/IL2Rg knockout swine to enable propagation. If successful, this project will lead to the first commercially available immunodeficient pig for regenerative medicine research and development.