Human hematopoiesis in genetically modified swine

Grant Project Details:

Ohad Gafni, PhD
Recombinetics Inc. | St Paul, MN
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Grant Location

Recombinetics Inc.
1246 University Ave W
St Paul, MN 55104

Grant Description

Our goal is to engineer a humanized swine model that carries key human cytokines, this strategy will provide the immunology field a high capacity and robust platform that promotes hematopoietic stem cells, CAR T cells, innate immune cells production, differentiated and cultured in high volume bioincubators. Humanized MISTRG porcine model could also become the new gold standard of immune response therapies before the final step of stage four of drug testing for human applications, altering the mouse as the commonly used model.

Grant Awardee Biography

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