MSC facilitated cartilage recycling for hip defects
Grant Project Details:
Awardee:
Aaron Krych, MD
Timeframe:
2022-2024
Location:
Mayo Clinic | Rochester, MN
Amount:
$470,224
Status:
In Process
Explore all RMM grants awarded since inception
Grant Description
The overall goal of this study is to test the safety and feasibility for a one-stage cartilage restoration procedure for symptomatic defects of the hip. This will be achieved using the patient’s own recycled cartilage cells combined with culture expanded allogeneic AMSCs (RECLAIM). We will assess 1) the local and systemic safety of this RECLAIM procedure, 2) improvement in pain and function in the target hip; and 3) the effect on bone and cartilage structures using MRI.