A multi-omics approach for the identification of species-specific developmental states and speed during interspecies chimerism

Grant Project Details:

Awardee:
Juan Carlos Rivera-Mulia, PhD
Timeframe:
2022-2024
Location:
University of Minnesota | Minneapolis , MN
Amount:
$250,000
Status:
In Process
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Grant Location

University of Minnesota
Minneapolis , MN

Grant Description

1. Construct integrative models that characterize the developmental states and rhythms of early embryogenesis.
2. Identify the developmental differences in host and donor cells in chimeric embryos of evolutionary close and distant species.
3. Identify key regulators of the developmental timing of host and donor cells in chimeric embryos.
4. Our long-term goal is to establish the basis for a better generation of human organs in host animals through interspecies chimerism.

Grant Awardee Biography

Dr. Rivera-Mulia