Purified Exosome Product for Rotator Cuff Repair and Regeneration

The overall goal of this project is to develop a novel biological therapy to treat rotator cuff tears, which is a common injury that causes shoulder pain and dysfunction. We will use a biological product extracted from human expired banked blood developed at Mayo Clinic and combine it with a fibrin glue that used in clinic to increase the rotator cuff healing capacity. We will test this drug effectiveness of treating rotator cuff tears using a rat model.