Ovarian mesenchymal stem cells

Grant Project Details:

Ilana Chefetz Menaker, PhD
University of Minnesota | Minneapolis, MN
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Grant Location

University of Minnesota
Minneapolis, MN 55414

Grant Description

Young women who undergo chemotherapy for cancer may face infertility. Our experiments are designed to learn how chemotherapy affects the ovaries. We propose to characterize murine ovarian mesenchymal stem cells and identify sub‐populations with enhanced differentiation capacity inside (multipotent) and outside (pluripotent) of the mesoderm. We would like to define these cells using single cell sequencing and characterize their regenerative capacity using a murine model of chemotherapy‐induced of ovarian dysfunction.

Grant Awardee Biography

image of Ilana Chefetz Menaker, PhD