Phase I study of delivery of autologous bone marrow derived mononuclear cells to myopathic right ventricle in patients with Ebstein anomaly during surgical intervention

Grant Project Details:

Awardee:
Kimberly Holst, MD
Timeframe:
2016-2018
Location:
Mayo Clinic | Rochester, MN
Amount:
$500,000
Status:
In Process
Explore all RMM grants awarded since inception

Grant timeline: proposal, updates, reports

Grant Location

Mayo Clinic
200 1st St SW
Rochester, MN 55905

Grant Description

The goal of this Phase I study is to establish the safety and feasibility of intramyocardial injection of autologous bone marrow derived mononuclear cells (BM-MNC) into the myopathic right ventricle of patients with Ebstein anomaly (EA) at time of elective cardiac surgery.

In no-cost extension to enroll additional patients in study

Read Holst’s most recent NCE Interim Progress Report here

Grant Awardee Biography

image of Kimberly Holst, MD

Dr. Holst is a general and thoracic surgery resident at Mayo Clinic and a resident in the Clinician Investigator Training Program.