Development of a Cellular Therapy for Parkinson's Disease

Our overall goal is to develop a cell therapy product for the treatment of Parkinson's disease.  In the present proposal we will evaluate critical aspects of our manufacturing process to insure a consistent product that will ultimately be suitable for therapeutic use and improve the quality of life for patients afflicted by this disease.

Superior Organoid Technologies
Timothy D. O'Brien, DVM, PhD
2018-2019

Development of a Perfusion-Based Testing System to Evaluate Short-Term Function in Bioengineered Kidney Grafts

Miromatrix is working to create a new source of kidney grafts for thousands of patients suffering from kidney failure who are wait-listed for transplantation. Through patented perfusion decellularization and recellularization technology, we are able to engineer new kidney grafts that combine pig-derived scaffolds with human kidney cells. The goal of this project is to design and develop a prototype perfusion system to test function in our bioengineered kidney grafts.

Miromatrix Medical Inc.
Joseph S. Uzarski, PhD
2018-2019

Medical Student Summer Research Program in Regenerative Medicine – Bridge to T35

We are training the next generation of Minnesota physicians to be skilled researchers. Year 1 Medical students will be immersed in outstanding laboratories at the University of Minnesota involved with research in Regenerative Medicine. The students will be followed through their careers, and the impact of this educational program on their future research activities will be assessed.

University of Minnesota Twin Cities
Troy C. Lund, MD, PhD
2018-2019

Minnesota Regenerative Medicine Education and Outreach Program (MRMEOP)

The mission of the Minnesota Regenerative Medicine Education and Outreach Program (MRMEOP) is to facilitate the understanding and integration of foundational concepts in regenerative medicine for underrepresented students and members of the community through expansion of educational, training, and career opportunities in Minnesota.

Macalester College
Randy S. Daughters, PhD
2018-2019

Innovators of the Future: Community Based Science Program, Grand Portage Band of Lake Superior Chippewa

Encourage Native American youth to achieve high school graduation and pursue post-­secondary education in order to secure a future career in regenerative medicine-focused biomedical science, research or health profession. This will be accomplished by increasing confidence and comfort regarding science and math and increasing awareness of K-­6th grade Native American youth regarding advanced education and careers in biomedical science and research.

Oshki Ogimaag Community School
Anna Wirta Kosobuski
2018-2019

Explore STEM: Reducing Barriers, Career Exploration, and Networking

Through the implementation of three outreach programs, the goals of this project are to foster an interest in Science, Technology, Engineering, and Mathematics (STEM) and encourage continued learning and growth in these areas. The aims of this project are to:

  • Increase the number of youth from diverse populations learning about STEM-related fields and careers.
  • Foster youth enthusiasm and interest for STEM-related fields and careers.
Minnesota State Engineering Center of Excellence
Melissa A Huppert, PhD
2018-2019
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