RMM Grants Awarded

See where grants have been awarded across Minnesota.
Kevin Loutherback, PhD
Automated Microfluidic Platform for Decentralized CAR-T Manufacturing
CAR-T cell therapy has become one of the most significant success stories in regenerative medicine over the past decade. However, its high cost…
2023 - 2025
Sarah Greising, PhD
Improving regeneration of traumatic muscle injuries through an activated muscle graft
Skeletal muscle plays a vital role in movement, body temperature regulation, and overall metabolism. Injuries to skeletal muscle can lead to…
2023 - 2024
Darko Bosnakovski, DVM, PhD
To evaluate the effect of senolytics on muscle regeneration in an FSHD animal model
Facioscapulohumeral muscular dystrophy (FSHD) is a relatively common progressive muscle disease. Recent research by the team suggests senescence (…
2023 - 2025
Nobuaki Kikyo, MD, PhD
Inhibition of cell reprogramming by inflammatory macrophages
Reprogramming one type of cell into another has gained significant interest as a potential strategy for regenerative medicine. However, current…
2023 - 2025
Mei Bigliardi-Qi, PhD
Light induced circadian control of epithelial stem cell differentiation for skin regeneration
Skin stem cells are crucial for wound healing and play a key role in skin conditions such as atopic dermatitis and psoriasis. These stem cells are…
2023 - 2025
Rory Smoot, MD
Androgen Receptor Blockade to Augment Liver Regeneration
A liver resection, or hepatectomy, is a surgical procedure to remove part of the liver. Post-hepatectomy liver failure is a major complication, with…
2024-2026
Nicole Shirkey-Son, PhD
Functional Correction of Mucopolysaccharidosis Type I (Hurler Syndrome) Using Genetically Modified Autologous Memory T Cells
This study aims to develop safer and more effective therapies for patients with a class of genetic diseases, called enzymopathies resulting from…
2024-2026
Sahar Saddoughi, MD, PhD
Use of Human Lung Exosomes to Prevent Ischemia/Reperfusion Injury in Lung Transplantation
This study aims to mitigate ischemia reperfusion injury (IRI), a major cause of primary graft dysfunction in lung transplants, by using an FDA-…
2024-2026
Omar Gutierrez Ruiz, PhD
Optimized Chimeric Antigen Receptor T Cell Therapy for Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer in Minnesota, yet current treatments for advanced CRC have low survival rates. This project…
2024-2026
Scott Riester, MD, PhD
Rotator Cuff Regeneration Using BMP5
Rotator cuff disease causes severe shoulder pain and limited arm movement. Current treatments offer temporary relief but do not regenerate damaged…
2024-2026
Erik Finger, MD, PhD
Cryopreservation of Pancreatic Islets to Achieve Diabetes Cure through Transplantation
Diabetes is a debilitating disease that has a tremendous impact on a person's health and wellbeing. Pancreatic islet transplantation offers a…
2024-2026
Bryce Beverlin II, PhD
Feasibility of Reducing Inflammation and Lung Injury to Regenerate Lung Tissue Using an Extracellular Biotherapeutic Aerosol in a Model of Acute Respiratory Distress Syndrome (ARDS)
Acute respiratory distress syndrome (ARDS) is a severe form of lung injury and a common cause of respiratory failure. Effective drug therapies that…
2024-2026