See where grants have been awarded across Minnesota.
Osteoarthritis (OA) is the most common form of arthritis and a leading cause of doctor visits, chronic disability, and joint pain. OA occurs when…
2022-2024
The goal of this project is to study the process of cardiac maturation, which involves changes that happen in the heart from birth to adulthood.…
2022-2024
The project aims to develop and test a novel method to create replacement blood vessels that are rapidly seeded with cells derived from a simple…
2022-2024
1. Construct integrative models that characterize the developmental states and rhythms of early embryogenesis.
2. Identify the developmental…
2022-2024
This application examines the mechanisms by which targeting the molecule YAP with medications can facilitate liver regeneration. We propose that YAP…
2022-2024
This proposal focuses on leveraging advances in cardiac stem cell biology to forge new therapeutic modalities for combating heart disease, the…
2022-2024
Congenital hydrocephalus is a major cause of childhood morbidity. Mutations in Trim71, a conserved stem-cell-specific RNA-binding protein, cause this…
2022-2024
Dry Age related macular degeneration is a chronic disease of aging that causes progressive loss
of vision due to damage to the RPE cell layer in the…
2022-2024
The overall goal of this study is to test the safety and feasibility for a one-stage cartilage restoration procedure for symptomatic defects of the…
2022-2024
To procure and optimize processing of human hepatocytes for research and clinical purposes.
2021-2022
The goal of this project is develop a platform for engineering cells from non-autologous sources for cell therapy. We will use a transposon-based non…
2021-2022
Our goal is to develop a therapeutic product that can arrest or reverse the progress of osteoarthritis of the knee, delay or obviate the need for…
2021-2022