RMM Grants Awarded

See where grants have been awarded across Minnesota.
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Ricardo Battaglino, PhD
Netrin-1 to Promote Locomotor Recovery in Chronic SCI
The goal of this project is to test the efficacy of intraspinal administration of the protein Netrin-1 (NTN1), as a therapeutical approach to promote…
2022-2024
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Chunfeng Zhao, MD
Purified Exosome Product for Rotator Cuff Repair and Regeneration
The overall goal of this project is to develop a novel biological therapy to treat rotator cuff tears, which is a common injury that causes shoulder…
2022-2024
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Jennifer Westendorf, PhD
Development Of Novel Proteolytic Targeting Chimeras That Promote Cartilage Regeneration
Osteoarthritis (OA) is the most common form of arthritis and a leading cause of doctor visits, chronic disability, and joint pain. OA occurs when…
2022-2024
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Jop van Berlo, MD, PhD
Unraveling Cardiac Maturation to improve Congenital Heart Disease Therapies
The goal of this project is to study the process of cardiac maturation, which involves changes that happen in the heart from birth to adulthood.…
2022-2024
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Robert Tranquillo, PhD
Rapidly Endothelialized Vascular Bypass Grafts From Autologous Adipose Microvessels
The project aims to develop and test a novel method to create replacement blood vessels that are rapidly seeded with cells derived from a simple…
2022-2024
Juan Carlos Rivera-Mulia, PhD
Juan Carlos Rivera-Mulia, PhD
A multi-omics approach for the identification of species-specific developmental states and speed during interspecies chimerism
1. Construct integrative models that characterize the developmental states and rhythms of early embryogenesis. 2. Identify the developmental…
2022-2024
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Rory Smoot, MD
Augmenting Liver Regeneration at the Single Cell Level
This application examines the mechanisms by which targeting the molecule YAP with medications can facilitate liver regeneration. We propose that YAP…
2022-2024
Joseph Metzger, PhD
Joseph Metzger, PhD
Advancing a genetically edited biosensor platform in human induced pluripotent stem cell-derived cardiac muscle for personalized medicine and drug discovery
This proposal focuses on leveraging advances in cardiac stem cell biology to forge new therapeutic modalities for combating heart disease, the…
2022-2024
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Qiuying Liu, PhD
Mechanistic studies on a congenital hydrocephalus causing mutation in Trim71
Congenital hydrocephalus is a major cause of childhood morbidity. Mutations in Trim71, a conserved stem-cell-specific RNA-binding protein, cause this…
2022-2024
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James Dutton, PhD
Pre-clinical evaluation of drug treatments to prevent vision loss from Dry Age-Related Macular Degeneration using patient-derived iPSC-RPE
Dry Age related macular degeneration is a chronic disease of aging that causes progressive loss of vision due to damage to the RPE cell layer in the…
2022-2024
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Aaron Krych, MD
MSC facilitated cartilage recycling for hip defects
The overall goal of this study is to test the safety and feasibility for a one-stage cartilage restoration procedure for symptomatic defects of the…
2022-2024
Robert Kaiser
Robert Kaiser, PhD, DABT
Isolation of primary human hepatocytes for expansion in a bioincubator
To procure and optimize processing of human hepatocytes for research and clinical purposes.
2021-2022